<p>Myasthenia gravis is a rare chronic autoimmune neuromuscular disease<br />This condition occurs more in women than men at any age<br />Myasthenia gravis literally means grave muscle weakness.<br />Antibodies blocks the neurotransmitter junction, causing a neuromuscular illness</p><p>The thymus gland may give incorrect instructions to developing immunity<br />This results in the production of the acetylcholine receptor antibodies.<br />Which unfortunately block the receptors at the neuromuscular junction<br />This result in the receptors unable to generate a muscle contraction</p><p>The muscle weakness usually increases during periods of activity<br />There is weakness of the eye, neck, limbs and fatigue<br />There is slurred speech and difficulty in swallowing<br />There may a waddling gait and difficulty in breathing</p><p>Treatment for myasthenia gravis is with anticholinesterase agents such as neostigmine<br />Immunosuppressive drugs such as prednisone, cyclosporine, and azathioprine<br />Thymectomy reduces symptoms in more than 70 percent of patients surgically<br />Plasmapheresis in which intravenous immune globulin replaces the abnormal antibodies</p><p>-An original poem by Kenneth Kee</p><p>Interesting Tips about the Myasthenia Gravis</p><p>A Healthy Lifestyle</p><p>1. Take a well Balanced Diet</p><p>2. Treatment for myasthenia gravis has improved tremendously with several therapies to help reduce and improve muscle weakness.</p><p>a. Anticholinesterase agents such as neostigmine and pyridostigmine which help improve neuromuscular transmission and increase muscle strength.</p><p>b. Immunosuppressive drugs such as prednisone, cyclosporine, and azathioprine improve muscle strength by suppressing the production of abnormal antibodies.</p><p>They must be used cautiously because of their many side effects.</p><p>c. .Thymectomy, the surgical removal of the thymus gland (usually abnormal in myasthenia gravis), reduces symptoms in more than 70 percent of patients and may cure some individuals, possibly by re-balancing the immune system.</p><p>d. Plasmapheresis in which abnormal antibodies are removed from the blood, and high-dose intravenous immune globulin which temporarily modifies the immune system and provides the body with normal antibodies from donated blood.</p><p>3. Keep bones and body strong</p><p>Bone marrow produces our blood</p><p>Eat foods rich in calcium like yogurt, cheese, milk, and dark green vegetables.</p><p>Eat foods rich in Vitamin D, like eggs, fatty fish, cereal, and fortified milk.</p><p>Eat food rich in Vitamins B and C such as green vegetables and fruits</p><p>Zinc and other minerals are important to the body</p><p>4. Get enough rest and Sleep</p><p>Avoid stress and tension</p><p>5. Exercise and stay active.</p><p>It is best to do weight-bearing exercise such as walking, jogging, stair climbing, dancing, or lifting weights for 2? hours a week.</p><p>One way to do this is to be active 30 minutes a day at least 5 days a week.</p><p>Begin slowly especially if a person has not been active.</p><p>6. Do not drink more than 2 alcohol drinks a day for a man or 1 alcohol drink a day for a woman.</p><p>Alcohol use also increases the chance of falling and breaking a bone.</p><p>Alcohol can affect the neurons and brain cells.</p><p>7. Stop or do not begin smoking.</p><p>It also interferes with blood supply and healing.</p><p>Chapter 1</p><p>Myasthenia Gravis</p><p>What is Myasthenia gravis?</p><p>Myasthenia gravis is a rare chronic autoimmune neuromuscular disease that causes weakening of the skeletal muscles of the body.</p><p>The name myasthenia gravis literally means grave muscle weakness.</p><p>How does Myasthenia Gravis develop?</p><p>Myasthenia gravis interferes in the transmission of nerve impulses to muscles.</p><p>Normally the nerve endings release a neurotransmitter substance called acetylcholine which then travels to the neuromuscular junction.</p><p>The acetylcholine binds to acetylcholine receptors which are activated and generate a muscle contraction.</p><p>In myasthenia gravis, antibodies produced by the body's immune system block, alter, or destroy the receptors for acetylcholine at the neuromuscular junction and prevent muscle contraction.</p>画面が切り替わりますので、しばらくお待ち下さい。

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